Diet and food allergy development during infancy: Birth cohort study findings using prospective food diary data

Diet and food allergy development during infancy: Birth cohort study findings using prospective food diary data

Kate E.C. Grimshaw, Joe Maskell, Erin M. Oliver, Ruth C.G. Morris, Keith D. Foote, E. N. Clare Mills, Barrie M. Margetts, Graham Roberts

Background After an era of only considering the allergenic properties of the infant diet and allergy outcomes, emerging data suggest that the overall composition of the infant diet might be a more important factor in the development of allergic disease.

Objective We sought to assess the relationship between infant dietary patterns in the first year of life and development of food allergy by age 2 years.

Methods We performed a nested, case-control, within-cohort study. Mothers kept prospective food diaries for the first year of life, with resultant diet data coded in a unique manner to produce new variables, which were then analyzed by using principal component analysis to identify infant feeding patterns within the study subjects.

Results Principal component analysis of diet diary data from 41 infants given a diagnosis of food allergy based on results of double-blind, placebo-controlled food challenges in the first 2 years of life and their 82 age-matched control subjects provided an early infant diet pattern and an ongoing diet pattern. There was no difference between the study groups for the early infant diet pattern, but for the ongoing diet pattern, there was a significant difference between the groups (P = .001). This ongoing dietary pattern was characterized by higher intake of fruits, vegetables, and home-prepared foods, with control infants having a significantly higher healthy infant diet dietary pattern score than children who had a food allergy.

Conclusions An infant diet consisting of high levels of fruits, vegetables, and home-prepared foods is associated with less food allergy by the age of 2 years.

Key words: Food allergy, double-blind, placebo-controlled food challenge, principal component analysis, infant feeding, prospective food diary data

 

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Current Allergy Immunology by Widodo Judarwanto

Gejala Alergi pada bayi dan anak justru paling sering dipicu oleh adanya infeksi khususnya infeksi virus. Tetapi sebaliknya saat itu sering dianggap karena alergi susu atau alergi makanan. Gejala infeksi virus pada bayi khususnya sulit dikenali karena mirip gejala alergi. Reaksi terhadap alergi susu atau alergi makanan biasanya relatif ringan, namun begitu dipicu infeksi manifestasinya lebih berat. Pemicu alergi tidak akan berarti bila penyebab alergi dihindari. Widodo Judarwanto 2012
The doctor of the future will give no medicine, but will instruct his patient in the care of the human frame, in diet and in the cause and prevention of disease.
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ALLERGY ONLINE CLINIC FOR CHILDREN, TEEN AND ADULT Yudhasmara Foundation www.allergyclinic.me   GROW UP CLINIC I JL Taman Bendungan Asahan 5 Jakarta Pusat, Jakarta Indonesia 10210 Phone : (021)  5703646 – 44466102 GROW UP CLINIC II  MENTENG SQUARE Jl Matraman 30 Jakarta Pusat 10430 phone 44466103 – 97730777 http://growupclinic.com  http://www.facebook.com/GrowUpClinic Creating-hashtag-on-twitter@growupclinic Working together support to health of all by clinical practice, research and educations. Advancing of the future pediatric and future parenting to optimalized physical, mental and social health and well being for fetal, newborn, infant, children, adolescents and young adult

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Curriculum Vitae Widodo Judarwanto

We are guilty of many errors and many faults. But our worst crime is abandoning the children, neglecting the fountain of life.
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